Scholasticism, came to an end about the time of the Black Death, and the initial period of the subsequent Italian Renaissance is sometimes seen as a lull in scientific activity. The Northern Renaissance, on the other hand, showed a decisive shift in focus from Aristoteleian natural philosophy to chemistry and the biological sciences (botany, anatomy, and medicine). Thus modern science in Europe was resumed in a period of great upheaval: the Protestant Reformation and Catholic Counter-Reformation; the discovery of the Americas by Christopher Columbus; the Fall of Constantinople; but also the re-discovery of Aristotle during the Scholastic period presaged large social and political changes.
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